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KMID : 0358819850120020129
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Journal of Korean Society of Plastic and Reconstructive Surgeons
1985 Volume.12 No. 2 p.129 ~ p.137
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AN EXPERIMENTAL COMPARISON OF AUTOGENOUS VEIN GRAFT, SILICONE TUBE IMPLANTATION, AND ARTERIAL ALLOGRAFT IN SMALL ARTERIAL DEFECT
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Park Seung-Ha
Kim Woo-Kyung
Chung Chun-Eun
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Abstract
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In many microvascular surgery, vascular replacement of small artery is often necessary due to arterial defect or tension, and autogenous vein graft has been widely used. But graft has some problems such as aneurysm formation, presence of valve, need much time, difficulites in gain of sufficient length and proper diameter,and stenosis tue to thickening of vessel.
The use of vascular prosthesis has been increased, but the complications such as hemorrhage, infection, and thrombosis were reported by many authors. The diameter of vascular prosthesis is smaller, the occlusion rate tue to thrombosis is higher, and clinically the vascular prosthesis has not been used in small arterial defect.
In this experimental studies, the arterial defect was made by excision of carotid artery of rat which its average external diameter is 1.2mm, and this was replaced with 4 different methods. 80 rats were divided into 4 groups as following.
1. Autogenous vein graft from femoral vein.
2. Implantation of silicone tube which its internal diameter is 1.0mm
3. Arterial allograft not preserved in alcohol.
4. Arterial allograft preserved in alcohol.
The patency rate and histologic changes are observed at postoperative 3 days, 1 week ,2 weeks and 3 weeks, and the results are as followings;
1. The patency rate is the highest in autogenous vein graft group(89%) and the lowest in silicone tube implant group(53%)
2. The aneurysm formation is most frequently noted in autogenous vein graft group(37%)
3. The occlusion due to thrombosis is the most frequent in silicone tube implant group(47%)
4. Arterial allograft preserved in alcohol is more patent, and less foreign body reaction than arterial allograft not preserved in alcohol.
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KEYWORD
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